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Tissue Transglutaminase IgA (TTG) detects auto-antibodies that can point towards an autoimmune condition and usually guides further, more specific testing.
Also known as: tTG-IgA, Celiac Disease Antibody
Sample
Blood
Fasting
Not required
Report in
24 hours
Collection
Free at home
The Tissue Transglutaminase IgA (tTG-IgA) test is the primary blood test used to screen for coeliac disease, an autoimmune condition triggered by gluten that damages the small intestine.
Ordered to investigate symptoms suggestive of coeliac disease - chronic diarrhoea, bloating, unexplained weight loss, iron-deficiency anaemia, or fatigue - especially when these persist despite other explanations.
It can help your doctor assess
Coeliac disease.
This test may be considered for:
Anyone with chronic gastrointestinal symptoms, unexplained iron-deficiency anaemia, or a family history of coeliac disease.
Whether this test is right for you depends on your symptoms, medical history and the reason for testing - your doctor can advise.
IgA antibodies against tissue transglutaminase, an enzyme targeted by the immune system in coeliac disease.
tTG-IgA
Coeliac Screening
The most sensitive and specific first-line blood test for coeliac disease; a positive result is typically confirmed with a small intestine biopsy.
How to read your result
Your report should be read using the reference interval, unit and method shown by the performing laboratory. A result outside a reference interval does not automatically establish a diagnosis, and a result inside the interval does not rule out every health problem. Clinical interpretation depends on symptoms, history and other findings.
| Marker | Result | What it may be associated with |
|---|---|---|
| tTG-IgA | Positive | Strongly suggests coeliac disease - your doctor will typically recommend a small intestine biopsy to confirm the diagnosis. |
If a result is outside the range
If the Tissue Transglutaminase IgA (TTG) is reported as high, low, positive, negative or otherwise outside the laboratory's stated interval, the meaning depends on the specific test and the reason it was ordered. Your clinician may consider repeat testing, related investigations or other clinical information before deciding what the result means.
Limitations of this test
A negative result in someone already on a gluten-free diet is unreliable - accurate testing requires continued gluten intake before the blood draw.
An abnormal result does not by itself mean you have a particular disease. Your doctor interprets results together with your symptoms, history and other tests.
| Parameter | Reference range | Unit |
|---|---|---|
| tTG-IgA | Negative (less than 20, lab-dependent) | U/mL |
Typical adult ranges for guidance. Reference intervals vary with the laboratory method, age and sex - always read your result against the range printed on your own report.
Book
Choose the test and a time slot online, or call us and we'll book it for you.
Prepare
Follow the preparation steps above for this test.
Sample collection
A trained phlebotomist collects the sample at your home - no extra charge.
Laboratory processing
Your sample is processed in our laboratory and reviewed by a pathologist.
Report
Your report is shared on WhatsApp and email, usually within 24 hours.
For a blood-based test, a small blood sample is collected by a trained healthcare professional, usually from a vein in the arm. The collection normally takes only a few minutes; mild temporary discomfort or bruising can occur at the puncture site.
This test must be done while you are still eating gluten - stopping gluten before testing can cause a false-negative result. People with selective IgA deficiency (a separate condition) can also get falsely low results.
Laboratory results are interpreted together with your symptoms, medical history and other investigations. If your results are significantly abnormal, or you have symptoms that worry you, discuss them with a qualified doctor promptly.
Trusted public health sources for the information on this page:
This information is for general awareness and does not replace advice from your doctor.
The TTG test cost in Mumbai at HWP Diagnostic is ₹1,449 - 26% less than the MRP of ₹1,949. There are no extra charges for home sample collection. The same price applies across Malad, Kandivali, Borivali and Goregaon.
| Test | Tissue Transglutaminase IgA (TTG) |
|---|---|
| Price at HWP Diagnostic | ₹1,449 |
| MRP | ₹1,949 (you save ₹500 - 26% off) |
| Home collection charge | Free |
| Report time | 24 hours |
| Fasting | Not required |
| Available in | Malad, Kandivali, Borivali & Goregaon (same price) |
Book the TTG test with free home sample collection anywhere in Malad, Kandivali, Borivali and Goregaon, or walk in to our lab in Malad West, Mumbai - open 24×7.
Home collection areas include
Malad WestMalwani & KharodiMalad EastKandivali WestKandivali EastBorivali WestGorai & Borivali WestIC Colony & MandapeshwarBorivali EastGoregaon WestBangur Nagar & Motilal NagarGoregaon EastAarey ColonyDahisarJogeshwari WestJogeshwari East
Directions on Google MapsThe full form of TTG is Tissue Transglutaminase IgA. It is also known as tTG-IgA, Celiac Disease Antibody.
Home collection at the same price (₹1,449) across these areas, with our lab in Malad West open 24×7.
Get this test along with other important checks - usually for less than booking them separately.
Yes, it’s important to continue eating gluten-containing foods before this test - stopping gluten beforehand can cause a false-negative result even with true coeliac disease.
No fasting is required.
Your doctor will typically recommend a small intestine biopsy to confirm the coeliac disease diagnosis before starting a gluten-free diet.
Tissue Transglutaminase IgA (TTG) is a blood test. Tissue Transglutaminase IgA (TTG) detects auto-antibodies that can point towards an autoimmune condition and usually guides further, more specific testing.
The Tissue Transglutaminase IgA (TTG) may be ordered when a healthcare professional needs information about the condition or health area assessed by this test. Tissue Transglutaminase IgA (TTG) detects auto-antibodies that can point towards an autoimmune condition and usually guides further, more specific testing. At HWP Diagnostic the sample can be collected free at your home in Malad and nearby Mumbai areas, and the report is usually shared within the same day or next day. Please carry or upload your doctor's prescription where the test needs one, and discuss the result with your doctor for a full interpretation.
Tissue Transglutaminase IgA (TTG) detects auto-antibodies that can point towards an autoimmune condition and usually guides further, more specific testing.
The test may be relevant for people whose symptoms, medical history, screening needs or treatment monitoring match the purpose of the Tissue Transglutaminase IgA (TTG).
No special preparation is needed for this test.
No, fasting is not required for the Tissue Transglutaminase IgA (TTG). You can eat and drink normally unless your doctor has advised otherwise.
The Tissue Transglutaminase IgA (TTG) is done on a blood sample.
For a blood-based test, a small blood sample is collected by a trained healthcare professional, usually from a vein in the arm. The collection normally takes only a few minutes; mild temporary discomfort or bruising can occur at the puncture site.
Reports for the Tissue Transglutaminase IgA (TTG) are usually ready within 24 hours of sample collection. You receive them on WhatsApp and email.
The Tissue Transglutaminase IgA (TTG) costs Rs 910 at HWP Diagnostic (MRP Rs 1210). Home sample collection is free.
Your report should be read using the reference interval, unit and method shown by the performing laboratory. A result outside a reference interval does not automatically establish a diagnosis, and a result inside the interval does not rule out every health problem. Clinical interpretation depends on symptoms, history and other findings.
If the Tissue Transglutaminase IgA (TTG) is reported as high, low, positive, negative or otherwise outside the laboratory's stated interval, the meaning depends on the specific test and the reason it was ordered. Your clinician may consider repeat testing, related investigations or other clinical information before deciding what the result means.
The Tissue Transglutaminase IgA (TTG) can provide important information, but laboratory results are generally interpreted together with symptoms, medical history, examination and other investigations. A single result should not be treated as a diagnosis without clinical context.
Some medicines, supplements, food, exercise and other pre-test factors can affect particular laboratory results. Tell the healthcare professional about medicines and supplements you take, and do not stop prescribed medicines unless your clinician tells you to.
Yes. Free home sample collection for the Tissue Transglutaminase IgA (TTG) is available across Malad, Kandivali, Borivali and Goregaon in Mumbai. You can also visit our Malad West lab, open 24x7.